Repeated attacks to the skin barrier can damage it, leading to water loss, increased permeability and, over time, premature aging. Lucas Meyer Cosmetics, in collaboration with the Infinity Institute, discovered a new protein: LCE6A known to be essential for mechanical resistance of corneocytes. By mimicking LCE6A activity, Corneopeptyl™ strengthens the corneocyte envelope resulting in a more resilient epidermal barrier with improved function, demonstrating reduction of permeability and water loss. Using AI and a patented algorithm, Corneopeptyl™ was demonstrated to future-proof skin by reducing the appearance of aging signs, with a rejuvenating effect of up to 4 years younger. It is patented and obtained by green chemistry-based synthesis.