Trautec has successfully achieved scale production of recombinant collagen type XVII by fermentation with Pichia Pastories and the homology degree with human collagen type XVII is >90%. Cell experiments and ex-vivo skin model test results of SRHC Type XVII showed that the treatment of SRHC Type XVII can (1) promote cell migration and adhesion; (2) increase the expression level of fundamental proteins involved in basement membrane; (3) repair dermal–epidermal junction (DEJ) damage and significantly increase the endogenous expression level of collagen type XVII both at the transcriptional and translational level;(4)prevent hair loss and the efficacy is even better than minoxidil tincture in clinical trials.